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7-Ethynyl-7-deaza-dA (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 7-Deazapurine Nucleoside Phosphoramidites
7-Ethynyl-7-deaza-dA (ibu) CE-phosphoramidite
Catalog # CBT-P-140
Compound 7-Ethynyl-7-deaza-dA (ibu) CE-phosphoramidite
Chemical Name 7-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosyl]-4-[(methylpropanoyl)amino]-5-ethynyl-7H-pyrrolo[2,3-d]pyrimidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula C47H55N6O7P
Molecular Weight 846.95 g/mol
Properties Storage at -18°C

Duplex melting studies demonstrated that the ethynyl side chain has a positive influence on DNA duplex stability when introduced at the 7-position of 7-deazapurines. CBT-P-140 is a verstile compound for DNA functionalization.
Appearance Off-white foam
References P. Ding, D. Wunnicke, H-J. Steinhoff, F. Seela, Chem. Eur. J. 2010, 16, 14385.
QuantityPricing (EUR)
50 µmol 190,00
100 µmol 370,00
250 mg 800,00
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