7-Ethynyl-7-deaza-dA (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 7-Deazapurine Nucleoside Phosphoramidites
Catalog # |
CBT-P-140 |
Compound |
7-Ethynyl-7-deaza-dA (ibu) CE-phosphoramidite |
Chemical Name |
7-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosyl]-4-[(methylpropanoyl)amino]-5-ethynyl-7H-pyrrolo[2,3-d]pyrimidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Formula |
C47H55N6O7P |
Molecular Weight |
846.95 g/mol |
Properties |
Storage at -18°C
Duplex melting studies demonstrated that the ethynyl side chain has a positive influence on DNA duplex stability when introduced at the 7-position of 7-deazapurines. CBT-P-140 is a verstile compound for DNA functionalization. |
Appearance |
Off-white foam |
References |
P. Ding, D. Wunnicke, H-J. Steinhoff, F. Seela, Chem. Eur. J. 2010, 16, 14385. |
Quantity | Pricing (EUR) |
50 µmol |
190,00 €
|
100 µmol |
370,00 €
|
250 mg |
800,00 €
|
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