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5-Octadiynyl-dU CE-phosphoramidite
Modified Phosphoramidites , class Other modifications
5-Octadiynyl-dU CE-phosphoramidite
Catalog # CBT-P-120
Compound 5-Octadiynyl-dU CE-phosphoramidite
Chemical Name 1-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosyl]-5-(octa-1,7-diynyl)-uracil 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula C47H55N4O8P
Molecular Weight 834.94 g/mol
Properties Storage at -18°C

Duplex melting studies demonstrated that the octa-1,7-diynyl side chain has a positive influence on DNA duplex stability when introduced at the 5-position of pyrimidines. CBT-P-120 is a verstile compound for DNA functionalization.
Appearance Off-white foam
References F. Seela, V. R. Sirivolu, Helv. Chim. Acta 2007, 90, 535.
F. Seela, V. R. Sirivolu, P. Chittepu, Bioconjugate Chem. 2008, 19, 211.
QuantityPricing (EUR)
50 µmol 150,00
100 µmol 225,00
250 mg 400,00
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