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8-Aza-7-deaza-dG (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 8-Aza-7-deazapurine Nucleoside Phosphoramidites
8-Aza-7-deaza-dG (ibu) CE-phosphoramidite
Catalog # CBT-P-100
Compound 8-Aza-7-deaza-dG (ibu) CE-phosphoramidite
Chemical Name 1-[2-Deoxy-5-O-(4,4'-dimethoxytrityl)-ß-D-erythro-pentofuranosyl]-1,5-dihydro-6-[(isobutyryl)amino]-4H-pyrazolo[3,4-d)pyrimidin-4-one 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Formula C44H54N7O8P
Molecular Weight 839.92 g/mol
Properties Storage at -18°C

The phosphoramidite CBT-P-100 can be employed in solid-phase oligonucleotide synthesis under standard conditions. Oligonucleotide duplexes incorporating 8-aza-7-deaza-dG residues instead of dG show enhanced duplex stability compared to corresponding unmodified duplexes (Seela & Driller, 1988). As a constituent of oligonucleotides, 8-aza-7-deaza-dG shows similar properties as 7-deaza-dG, e.g. G-quartet formation is prevented.
Appearance Colorless foam
References F. Seela, H. Driller, Helv. Chim. Acta 1988, 71, 1191.
QuantityPricing (EUR)
50 µmol 150,00
100 µmol 280,00
250 mg 650,00
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