8-Aza-7-deaza-dG (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 8-Aza-7-deazapurine Nucleoside Phosphoramidites
Catalog # |
CBT-P-100 |
Compound |
8-Aza-7-deaza-dG (ibu) CE-phosphoramidite |
Chemical Name |
1-[2-Deoxy-5-O-(4,4'-dimethoxytrityl)-ß-D-erythro-pentofuranosyl]-1,5-dihydro-6-[(isobutyryl)amino]-4H-pyrazolo[3,4-d)pyrimidin-4-one 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Formula |
C44H54N7O8P |
Molecular Weight |
839.92 g/mol |
Properties |
Storage at -18°C
The phosphoramidite CBT-P-100 can be employed in solid-phase oligonucleotide synthesis under standard conditions. Oligonucleotide duplexes incorporating 8-aza-7-deaza-dG residues instead of dG show enhanced duplex stability compared to corresponding unmodified duplexes (Seela & Driller, 1988). As a constituent of oligonucleotides, 8-aza-7-deaza-dG shows similar properties as 7-deaza-dG, e.g. G-quartet formation is prevented. |
Appearance |
Colorless foam |
References |
F. Seela, H. Driller, Helv. Chim. Acta 1988, 71, 1191. |
Quantity | Pricing (EUR) |
50 µmol |
150,00 €
|
100 µmol |
280,00 €
|
250 mg |
650,00 €
|
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For bulk quantities request by e-Mail:
dna@chembiotech.de or phone: +49 251 53406 858 or +49 251 53406 505.