Catalog # | CBT-P-100 |
Compound | 8-Aza-7-deaza-dG (ibu) CE-phosphoramidite |
Chemical Name | 1-[2-Deoxy-5-O-(4,4'-dimethoxytrityl)-ß-D-erythro-pentofuranosyl]-1,5-dihydro-6-[(isobutyryl)amino] -4H-pyrazolo[3,4-d)pyrimidin-4-one 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite |
Formula | C44H54N7O8P |
Molecular Weight | 839.92 g/mol |
Properties | Storage at -18°C The phosphoramidite CBT-P-100 can be employed in solid-phase oligonucleotide synthesis under standard conditions. Oligonucleotide duplexes incorporating 8-aza-7-deaza-dG residues instead of dG show enhanced duplex stability compared to corresponding unmodified duplexes (Seela & Driller, 1988). As a constituent of oligonucleotides, 8-aza-7-deaza-dG shows similar properties as 7-deaza-dG, e.g. G-quartet formation is prevented. |
Appearance | Colorless foam |
References | F. Seela, H. Driller, Helv. Chim. Acta 1988, 71, 1191. |
Quantity | Pricing (EUR) |
50 µmol | |
100 µmol | |
250 mg |