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8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 8-Aza-7-deazapurine Nucleoside Phosphoramidites
8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Catalog # CBT-P-090
Compound 8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Chemical Name 1-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosy]-4-(isobutyrylamino)-1H-pyrazolo[3,4-d]pyrimidine 3'-[(2-cyanoethyl)-N,N-diisopropyl-phosphoramidite]
Formula C44H54N7O7P
Molecular Weight 823.92 g/mol
Properties Storage at -18°C

Phosphoramidite building blocks of 8-aza-7-deaza-2'-deoxyadenosine were first reported in 1988. Oligonucleotide duplexes maintain their stability, when dA is replaced by 8-aza-7-deaza-dA residues. Furthermore, oligonucleotides containing this nucleoside cannot form Hoogsteen base pairs, thereby reducing mismatch formation.
References F. Seela, K. Kaiser, Helv. Chim. Acta 1988, 71, 1813.
QuantityPricing (EUR)
50 µmol 150,00
100 µmol 280,00
250 mg 650,00
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