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8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Modified Phosphoramidites , class 8-Aza-7-deazapurine Nucleoside Phosphoramidites
8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Catalog # CBT-P-090
Compound 8-Aza-7-deaza-dA (ibu) CE-phosphoramidite
Chemical Name 1-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosy]-4-(isobutyrylamino)-1H-pyrazolo[3,4-d]pyrimidine 3'-[(2-cyanoethyl)-N,N-diisopropyl-phosphoramidite]
Formula C44H54N7O7P
Molecular Weight 823.92 g/mol
Properties Storage at -18°C

Phosphoramidite building blocks of 8-aza-7-deaza-2'-deoxyadenosine were first reported in 1988. Oligonucleotide duplexes maintain their stability, when dA is replaced by 8-aza-7-deaza-dA residues. Furthermore, oligonucleotides containing this nucleoside cannot form Hoogsteen base pairs, thereby reducing mismatch formation.
References F. Seela, K. Kaiser, Helv. Chim. Acta 1988, 71, 1813.
QuantityPricing (EUR)
50 µmol 150,00 €
100 µmol 280,00 €
250 mg 650,00 €
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