|Compound||7-Deaza-dA (ac) CE-phosphoramidite|
|Chemical Name||7-[2-Deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-ß-D-erythro-pentofuranosyl]-4-[(acetyl)amino]-7H-pyrrolo[2,3-d]pyrimidine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite|
|Molecular Weight||794.87 g/mol|
|Properties||Storage at -18°C
Oligonucleotides incorporating 2’-deoxytubercidin were first described in 1987. As the benzoyl protecting is too stable for cleavage under standard deprotection conditions, we offer isobutyryl and acetyl protecting groups which are compatible to solid-phase oligonucleotide synthesis. Absence of nitrogen-7 provides useful information in the detection of DNA-enzyme binding sites.
|References||F. Seela, A. Kehne, Biochemistry 1987, 26, 2232.
F. Seela, H. Berg, H. Rosemeyer, Biochemistry 1989, 28, 6193.